The B-imune Range of Drinks

The B-imune drinks are an affordable, nutritious and healthy diet supplement that include Probiotic, Prebiotic, L-Glutamine and other Nutraceutical contents, which improve the body's immune status, so limiting the risks of opportunistic diseases.

B-imune drinks are the most viable alternative to the myriad of nutritional supplements and micronutrients that are presented in their individual forms. B-imune is an “all-in-one” solution that provides a highly fortified nutritional supplement to anyone wanting to boost their immune status and supplement their diet.

Having positioned the range of B-imune drinks as being suitable for various nutritional supplementation requirements, it must however be stated that B-imune was originally formulated to address the nutritional needs of people with HIV/Aids, and offer a viable alternative in the treatment of general intestinal disorders.

The most important nutritional priority for people at the Aids (Acquired Immunodeficiency Syndrome) infection stage is fluid intake. The majority of HIV-related hospital admissions are for dehydration, with the most obvious fluid losses from diarrhea, vomiting and perspiration. Weight loss is usually the next symptom, and therefore energy is the next concern. Of the diet’s energy providers, fat, carbohydrate and protein, the best energy source is from fat, followed by carbohydrate and protein. Sufficient vitamins and minerals are obviously also essential in everyone’s diet (Jensen, 1994).

B-imune as a beverage, obviously contributes to the fluid losses associated with Aids infection. B-imune further serves the Aids patient with a carefully balanced source of protein, fat, carbohydrate, and essential amino acids.

Abstract of research thesis

The objective of this pilot study was to evaluate the effects of a new micronutrient, glutamine, pre- and probiotic enriched liquid nutritional supplement on the nutritional status and immunity of adults living with HIV/AIDS.

Done by Roy D Kennedy M Nutr(Stell), RD(SA)

B-imune is fortified with vitamins, bio-available minerals and also contains nutraceuticals.

B-imune Energy Drink

Ingredients Summary:

Maize starch, Soy protein, Sugar, Salt, Minerals, L-Glutamine, Vitamins, Taurine, L-Carnitine, Probiotics, Prebiotics, Flavourant and Colorant.

Preparation Directions:

Mix 200ml of cool or cold water or milk with 40g of B-imune, and dissolve by stirring/shaking.
B-imune can also be further diluted for people who have difficulty swallowing.

Recommended Usage:

Adults: 1 x 40g servings per day.
Children: 1 x 40g serving per day.

Packaging:

Typically 30 x 40g sachets per box.
Alternate packaging solutions are available dependant on customer requirements.

Nutritional Information:

	units	Per 100g
Protein (fat free basis)	g	22.8
Fat	g	12.8
Carbohydrates	g	54.60
Dietary Fibre	g	12.5
Energy Value	kj	1783
	Per Portion 40g	%RDA per portion
Vitamin A	1000 ug RE	100
Vitamin D3	5 ug	100
Vitamin E (7.45IU)	10 mg a TE	100
Ascorbic acid (Vitamin C)	60 mg	100
D-Biotin	100 ug	100
Folic acid	200 ug	100
Pantothenic acid	6 mg	101
Nicotinamide (Vitamin B3)	18 mg	101
Riboflavin (Vitamin B2)	1.6 mg	100
Thiamine (Vitamin B1)	1.4 mg	106
Pyridoxine (Vitamin B6)	2 mg	100
Cyanocobalamin (Vitamin B12)	1 ug	100
Iron (Ferrochel R *AA Chelate)	1.84 mg	13
Zinc (*AA Chelate)	2.6 mg	17
Chromium (*AA Chelavite)	0.2 mg	-
Selenium (*AA Chelate)	52.4 ug	-
Calcium	160 mg	20
Potassium	240 mg	-
Magnesium	29.2 mg	10
Manganese (*AA Chelazome)	0.52 mg	17
Copper	0.11 mg	-
Phosphorus	140 mg	18
L-Carnitine	84 mg
L-Glutamine	2 g
Taurine	140 mg
Probiotics	1 x 10^9 cfu
Prebiotics	3 g
Isoflavones: Diadzein	21.8 mg
Genistein	19.5 mg
Glycetein	14.4 mg
Lecithin	0.19 g

*Amino Acid
% RDA stated for persons 10 years and older.

B-imune Maize Drink

Ingredients Summary:

Maize starch, Soy protein, Sugar, Salt, Minerals, L-Glutamine, Vitamins, Taurine, L-Carnitine, Probiotics, Prebiotics, Flavourant and Colourant.

Preparation Directions:

Mix 200 - 250ml of cool or cold water or milk with 50g of B-imune, and dissolve by stirring/shaking.
B-imune can also be further diluted for people who have difficulty swallowing.

Recommended Usage:

Adults: 2 x 50g servings per day.
Children: 1 x 50g serving per day.

Packaging:

Typically 30 x 50g sachets per box.
Alternate packaging solutions are available dependant on customer requirements.

Nutritional Information:

	units	Per 100g
Protein (fat free basis)	g	17.0
Fat	g	7.2
Carbohydrates	g	54.7
Dietary Fibre	g	12.9
Energy Value	kj	1410
	Per Portion 50g	% RDA per portion
Vitamin A (1665IU)	500 ug RE	50
Vitamin D3	5 ug	50
Vitamin E (5.0IU)	10 mg a TE	50
Ascorbic acid	30.0 mg	50
D-Biotin	50 ug	50
Folic acid	100 ug	50
Pantothenic acid	3 mg	50
Nicotinamide (Vitamin B3)	9 mg	50
Riboflavin (Vitamin B2)	0.8 mg	50
Thiamine (Vitamin B1)	0.7 mg	50
Pyridoxine (Vitamin B6)	1 mg	50
Cyanocobalamin (Vitamin B12)	0.5 ug	50
Iron (Serrochel *AA Chelate)	2.1 mg	15
Zinc (*AA Chelate)	2.1 mg	15
Chromium (*AA Chelavite)	0.03 mg	-
Selenium (*AA Chelate)	8 ug	-
Calcium	120 mg	25
Potassium	244.8 mg	-
Magnesium	29.9 mg	15
Manganese (*AA Chelazome)	0.65 mg	15
Copper	0.28 mg	-
Phosphorus	175 mg	18
Carnitine	42 mg
L-Glutamine	1 g
Taurine	70 mg
Probiotics	1 x 10^9 cfu
Prebiotics	3 g
Isoflavones: Diadzein	21.8 mg
Genistein	19.5 mg
Glycetein	14.4 mg
Lecithin	0.19 g

*Amino Acid
% RDA stated for people 10 years and older.

The unique nutritional characteristics of B-imune:

Proteins

The protein fraction of B-imune is mainly derived from soy, although some is also obtained from maize. Soy protein is particularly valuable because its amino acid composition complements that of other cereals. Cereal based diets containing mixed sources of protein are most likely to be limiting in lysine, tryptophan and threonine. Adding soy protein to these diets will increase the amount of the latter amino acids and thus improve the amino acid profile, as well as the protein quality, which is measured as Protein Efficiency Ratio (PER).

Fats

The fat fraction of B-imune is mainly from soy oil. Soybean oil is highly digestible, high in polyunsaturated fatty acids and contains no cholesterol. Soy bean oil is composed of about 85% unsaturated fat, which is generally recognised as beneficial to health as opposed to saturated fat.

Probiotics

Probiotics are micro-organisms e.g. Lactobacillus and Bifidobacterium strains, that possess health promoting properties and can be defined as live food supplements which beneficially affect the host by improving the balance of intestinal microbial flora (Fuller, 1989). These are essentially friendly bacteria of the same family as that already living in our bowel. These bacteria have GRAS status meaning ‘generally regarded as safe’.

The gastrointestinal (GI) tract is exposed to food, water and any other preparations taken orally. It acts as a barrier to harmful substances and invasive infective pathogens. To compliment the GI as a physiological barrier, gut associated lymphoid tissue (GALT) is distributed throughout the GI tract and it is the largest lymphoid or immune organ in the body, accounting for approximately 80% of all immunoglobulin-producing cells in the body. Probiotics stimulate these GALT to produce immunoglobulin (IgA) resulting in an enhanced immune response during their presence (Horn, 1999; Hawkins, 1993).

When these beneficial resident bacteria are dominant in the digestive tract, they regulate the balance of the intestinal microflora, thus contributing to healthy digestion and overall well being. However, when these bacteria lose their dominant role, pathogenic bacteria, viruses and yeast’s begin to multiply with detrimental effects. The main factors, which cause the beneficial bacteria to lose their ability to maintain the necessary balance of the intestinal microflora, are:

• antibiotic treatment
• compromised immune system
• diarrhea
• incorrect diet
• stress
• environmental pollution
• steroid/hormone treatment
• impaired peristaltic action

In addition to the enhanced functioning of the immune system, other beneficial properties of probiotics include:

• the enhanced absorption of calcium, phosphorous and manganese
• the production of B-galactosidase (leading to an increased lactose tolerance)
• the detoxification of carcinogens
• the production of vitamins of the B group and vitamin K
• the lowering of blood cholesterol levels
• the lowering of blood ammonia levels

Clinical trials to prove the safety and efficacy of the probiotic strain Bifidobacterium, was reported by Haschke et al, 1998. This strain was selected because of its excellent survival during intestinal transit and adhesion to enterocytes. In another study by Pfeifer and Rosat, 1999, the Nestle scientists selected a Lactobacillus acidophilus strain with exceptional probiotic effects and the clinical evidence for the enhancement of the natural immunity of the gut, was summarised in this report. These two groups of microorganisms are closely associated with each other. Lactobacilli, which are microaerophilic, reduce the level of oxygen in their immediate surroundings, thus creating a favourable environment for Bifidobacteria, which are anaerobic inhabitants of the large intestine.

Successful re-colonization and restoration of a balance among the intestinal flora may require regular supplementation of the diet with large quantities of probiotic cultures. Regular consumption of B-imune contributes to the re-establishing of these beneficial resident bacteria in the intestine. B-imune is supplemented with Bifidobacterium bifidum and Lactobacillus acidophilus in equal quantities. The total bacterial count in B-imune is 1x10^9 colony forming units/g of product and exceed the proposed concept regulation of 1x10^7 colony forming units/g of product. Both these bacterial strains have been proved to survive the gut’s bile acids after ingestion.

Prebiotics

A prebiotic is defined as a non-digestible food ingredient that beneficially affects the host by selectively stimulating the growth and/or activity of one or more types of bacteria in the colon and that can improve the host's general health (Gibson, 1998).
B-imune contains fructo-oligosaccharides (FOS) which selectively promote the growth of the above-mentioned bacteria.

L-Glutamine

L-glutamine is the most abundant amino acid in the bloodstream and because human cells readily synthesise it, is usually considered a non-essential amino acid. However, during catabolic stress such as trauma, sepsis, starvation and chemotherapy, the intracellular glutamine levels can drop more than 50%, and it is under these circumstances that supplemental glutamine becomes necessary. Glutamine has therefore been re-classified as a conditionally essential amino acid.

The gastrointestinal tract is by far the greatest user of glutamine in the body, as enterocytes in the intestinal epithelium use glutamine as their principal metabolic fuel for growth and proliferation. Research has demonstrated that glutamine addition decreases intestinal permeability (Hwang, 1987; Liet, 1994) and also resulted in an improved gut barrier function, as well as immune activity in the gut (Khan, 1999; O’Flaherty 1999; Jian, 1999). HIV infection appears to induce glutamine deficiency, with the result of muscle protein wasting, particularly in the Aids stage of the infection (Shabert, 1996). Approximately 20 % of AIDS patients also have impaired intestinal permeability (Noyer, 1998). Clinical studies have demonstrated glutamine supplementation has significant benefit in these patients. Controlled studies with HIV-infected patients proved that L-glutamine supplements increased weight gain and improved immune status as evidenced by increased CD3 and CD8 cell counts, and decreased HIV viral load (Clark, 2000). Other proven benefits resulted in stabilisation of intestinal permeability and enhanced intestinal absorption (Noyer, 1998).

L-glutamine is thus an essential supplement choice for more chronic conditions of the GI, such as AIDS and Cancer patients, where the GI integrity has been compromised.

Taurine

Taurine is a conditionally essential amino acid that is found in the central nervous system and skeletal muscle, and is very concentrated in the brain and heart. Taurine is involved in a number of physiological processes. One of its pivotal roles is that it is essential for proper digestion of fats, absorption of fat-soluble vitamins and production of bile salts (Hardison, 1983; Mizushima, 1996). Individuals deficient in methionine or cysteine may have difficulty in manufacturing taurine and dietary intake is believed to be important.

Carnitine

Carnitine is a substance related to vitamin B. It holds a chemical structure similar to that of amino acids, which has been found to have a wide range of protective effects and health benefits when consumed in sufficient amounts. Carnitine increases fat metabolism, with a deficiency thereof leading to an inability to transport fatty acids into the mitochondria for oxidation. Energy provision from fat sources in the diet is thus enhanced by the addition of carnitine.

Nutraceuticals

Nutraceuticals are added ingredients contained within food products that have a health improving effect. Functional foods may be viewed as forming the borderline between general foods and pharmaceutical products (Fox, 1998). Dr Blum from F.Hoffmann-La Roche Ltd, Basel, Switzerland, listed the following degenerative diseases and suggested nutrients that may assist in their prevention (Nutrilit ,1997):

Disease.	Protective nutrients.
Coronary Heart Disease (CHD).	Linoleic- and linolenic acid, omega-3 and omega-6 fatty acids, vitamins C, E, carotenoids, flavonoids, folate, vitamins B6 and B12, potassium and magnesium.
Cancer.	Vitamin C (stomach), E (oesophagus), D (colon), calcium (colon), carotenoids (liver) and dietary fibre (colon).
Diabetes.	Foods with a low glycaemic index, vitamin E, chromium.
Stroke.	Vitamin E and A, fish oils, flavonoids.
Cataract & Macular degeneration.	Vitamin C, E, B complex and carotenoids.

A combination of nutraceutical antioxidants contained in B-imune, protect the human body against cell damage caused by free radicals. These components include - Ascorbic acid, Alpha-Tocopherol, Folate, Vitamin B6 and B12, Isoflavonoids and Selenium.

Summary:

High in Soy protein.	Soy protein offers excellent biological value and improves the amino acid profile. Protein is essential for normal growth, the building and regeneration of body tissue, normal immune function and to help maintain weight.
Contains Soy oil, Carnitine and Taurine.	Soybean oil is a highly digestible source of energy (calories), which is high in polyunsaturated fatty acids and contains no cholesterol. Energy provision from the fat sources in any diet is enhanced by the addition of Carnitine, which increases fat metabolism. Taurinre is essential for proper digestion of fats, absorption of fat soluble vitamins and the production of bile salts
Contains L-Glutamine.	Glutamine is an important fuel for the immune system and the cells in the intestinal tract. Glutamine addition decreases intestinal permeability, so improving the gut barrier function, as well as the immune activity within the gut.
Contains Probiotic intestiflora.	Bifidobacterium and Lactobacillus species stimulate immune functions, by altering the acidity of gut areas that are inhabited by invading or ‘unfriendly’ microbes, by producing antibiotic substances and by depriving ‘unfriendly’ microbes of their nutrients. Probiotics aid in mineral absorption, lactose digestion, and the synthesis of vitamins, whilst also preventing diarrhea.
Contains Prebiotics.	Contains fructo-oligosaccharides, which selectively stimulates the growth of Probiotic intestinal flora in the colon.
Includes Nutraceuticals.	Play a vital protective roll against cell damage caused by free radicals. Includes high levels of Vitamins and chelated Minerals. To effectively address the Recommended Daily Allowance (RDA), and especially the increased requirements of a compromised immune system.

NutriShake - High energy drink

Description

A nutritious and very tasty high energy drink/shake for use throughout the day. NutriShake is a popular school feeding scheme supplement.

Flavours

Vanilla, Strawberry and Banana.

Preparation Instructions

Mix 150g of powder with 1 litre of water or, mix 1 measure of powder with 4 parts of water. 1 Kg makes 6.7 litres or 33.5 portions of 200ml each.

Packaging

25kg, 10kg, 5kg, Woven polypropylene bags with polythene liner.

Also available in 1 kg sachets.

 

Typical analysis:		per 100g
Energy	kj	1960
Protein	g	15.8
Fat	g	20.0
Carbohydrates	g	61.6
Moisture	g	5.0
Vitamins:
33 % of RDA PER 30G PORTION (FOR PERSONS 10YRS AND OLDER)